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We found accumulated reactive oxygen species (ROS), increased lipid peroxidation and DNA damages in Mdr2 −/− MEFs.
Sixty Hz sinusoidal MF could significantly inhibit cell growth and induce apoptosis in prostate cancer cells by cleaved caspase-3 and accumulated reactive oxygen species [ 1].
Consequently, UBP10 inactivation induced a transcriptional oxidative stress response accompanied by a subpopulation of apoptotic cells which accumulated reactive oxygen species [ 14, 15].
Nodule separation into "daughter nodules" was initiated by the formation of necrotic layers at the future region of nodule separation which accumulated reactive oxygen species (ROS) as revealed by NBT staining.
Cellular processes that have been proposed to explain aging-induced sarcopenia include changes in hormone levels [ 2], inflammation-initiated impairment in protein synthesis and acceleration of protein degradation in muscle [ 3], responses to accumulated reactive oxygen species [ 4] and alterations in factors that regulate myogenesis [ 5].
The imbalance in quality control may be restricted to either a generic set of proteins or a subset of neuronal-specific proteins, which has higher tendency for aggregation due to oxidative modification of proteins by abnormally accumulated reactive dopamine adducts (52).
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Extract of Nostoc sp. induced oxidative stress by accumulating reactive oxygen species (ROS), causing massive cell death in Mimosa pigra (Sukkhaeng et al. 2015).
This process is called photoinhibition [17], and thereby accumulating reactive oxygen species (ROS) initiate the symbionts' antioxidant response.
An initial cerebral hypoxic and/or ischemic insult is characterised by a switch to anaerobic metabolism and accumulating reactive metabolites resulting in severe energy depletion.
Neural stem cells accumulate reactive oxygen species (ROS) during re-oxygenation and inhibition of ROS biosynthesis counteracts their proliferation as well as neurogenesis.
Metabolic stresses disturbs the mechanisms of DNA synthesis and repair by accumulating misfolded and aggregate-prone proteins, and triggers oxidative stress through accumulating reactive oxygen species (ROS -generating oROS -generatingcially mitorganelles
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