The phrase "accumulated impairment" is correct and usable in written English.
It can be used in contexts related to finance, accounting, or health, where it refers to the total amount of impairment that has been recognized over time.
Example: "The company's financial statements reflected an accumulated impairment of its assets due to prolonged market downturns."
Alternatives: "total impairment" or "cumulative impairment".
Although the mechanisms underlying this observation are not apparent from this study, one obvious factor is the effect of accumulated impairment of domain-general, distributed brain networks over the lifetime of any individual patient.
Other potential explanations for the empirically observed co-variation in hearing and cognitive function [ 11, 12] include (1) the common cause hypothesis [ 10, 41] and (2) accumulated impairment hypothesis.
The association between low IQ and adult schizophrenia observed in previous studies may be understood as an expression of accumulating neurodevelopmental impairment on the pathway to psychosis.
Thus, this hypothesis on AD pathogenesis claims that mitochondrial impairment may result from accumulated mtDNA damage that accompanies normal aging, amplified by disease-specific factors [9], [3].
Geriatric syndromes are multifactorial health conditions that occur when the accumulated effect of impairments in multiple systems renders a person vulnerable to situational challenges [ 5].
Dizziness in older persons has, due to its complexity, been described as a geriatric syndrome [ 4, 9], a multifactorial health condition that occurs when the accumulated effects of impairments in multiple systems render a person vulnerable to situational changes [ 9].
Many studies have reported that an accumulated sleep deprivation induces impairments of cognition, vigilance, and memory, and disturbances of mood [ 30- 33].
Accumulating evidence implicates impairment of the autophagy-lysosome pathway in Alzheimer's disease (AD).
Furthermore, we examined levels of p62/SQSTM1, a known autophagy substrate accumulating upon autophagy impairment [ 20].
Evidence has been accumulated that dysfunction of Tor results in impairment of overall protein synthesis[1].
Sadeh et al. [12] elucidated that such impairments might be caused by accumulated sleepiness due to sleep restriction, with some cognitive functions being vulnerable to accumulated sleepiness.
