The phrase "accumulated abnormalities" is correct and usable in written English.
It can be used in contexts discussing the build-up of irregularities or deviations from the norm, often in medical, scientific, or analytical discussions.
Example: "The patient's test results indicated a series of accumulated abnormalities that required further investigation."
Alternatives: "cumulative irregularities" or "gathered anomalies".
Accumulating abnormalities in glucose/lactate balance in combination with accelerated mitochondrial damage in neurons may be at the core of many cellular events in senescence and neurodegeneration, including the initiation and progression of LOAD15.
And over time some of the cells have accumulated genetic abnormalities that make them more difficult to use even for basic research.
Previously, a community-based study in South China Shanghaii) reported that retinopathy was highly associated with accumulated metabolic abnormalities.
An instigator initiating the inflammatory process has not been identified; however, overwhelming evidence has accumulated that abnormalities in innate and adaptive immunity play a critical role in the initiation and the perpetuation of the vasculitis.
Such accumulated Lewy abnormalities may have altered the axonal structure, resulting in FA values that were significantly lower in the major tracts in our PDD patients than in the controls.
Despite the multiple accumulated genetic abnormalities that cause malignant transformation, however, it is evident that some of the transformed cells can still respond to signals from their external environment.
Third, the microvascular abnormalities present in the retina may also be occurring in many other vascular beds, and CV outcomes may be due in part to accumulated microvascular abnormalities in the myocardial microcirculation, arterial wall (i.e., vasa vasorum), and elsewhere.
Tumour progression is a multistep process accumulating different abnormalities leading to expression and activation of genes participating in malignant progression.
It is considered that myeloma cells accumulate various abnormalities that contribute to disease progression from MGUS (Korde et al, 2011; Zingone and Kuehl, 2011).
Tumour progression is a multistage process in which tumour cells accumulate different abnormalities involving rearrangement, induction, or silencing of the cell-adhesion molecules (Fidler, 2002; Hirohashi and Kanai, 2003; Cavallaro and Christofori, 2004).
