Both models were shown to accumulate branched-chain amino acids in blood and urine.
These data are consistent with brain specific growth restriction and suggest that accumulating branched-chain amino acids compete with essential large neutral amino acida for brain access through the large neutral amino acid transporter (LAT1) (Killian and Chikhale, 2001).
Thus, a multitude of SNPs can accumulate along branches of a haplogroup, which may alter the significance of other sub-haplogroups; hence, the test for individual SNPs reveals an inadequate image of the evolutionary and functional role for mtDNA in an individual's haplotype [ 58].
For example, touch receptor neurons accumulate aberrant branching with age, whereas two of the nerve ring interneurons and some dopaminergic neurons remain intact.
If untreated, affected individuals accumulate substantial branched-chain amino acids, mostly leucine, and suffer encephalopathy within the first week of life as well as cerebral oedema and dysmyelination with chronic brain injury (Crome et al., 1961; Silberman et al., 1961; Chuang and Shih, 2001).
(ii) Horizontal branches accumulate more canopy soil than branches with a steeper inclination (Nadkarni and Matelson 1991).
The fact that lateral branches have a shorter lifespan than central shoots allows for the possibility that Na may accumulate in the branches, leading to their senescence.
Many plants accumulate dead, brown branches underneath healthy green growth.
Non-local branches accumulate the recombination rate until they are targeted by a coalescence.
It may be that multiple substitutions destroy synapomorphies (process of signal erosion), homoplasies can accumulate along "long branches".
In populations having gone through a recent and still large expansion, the internal branches should be very short due to the star-like structure of the tree, and a very few mutations would accumulate on those branches [ 40, 52].
