The phrase "accrued events" is not commonly used in written English and may cause confusion.
It could be used in contexts discussing events that have accumulated over time, particularly in financial or legal discussions.
Example: "The report details the accrued events that have impacted the company's financial standing over the past year."
Alternatives: "accumulated events" or "gathered events".
In CAPRICORN, the introduction of a composite co-primary outcome subsequent to review of interim data can be seen as an attempt to achieve a positive trial by using a composite endpoint which would have a higher likelihood of accruing events.
In general, data associated with the longest follow-up was retained; however, in instances where patient groups within the same study had variable lengths of follow up, estimates were made for all groups at the shortest time point to allow all groups equivalent time to accrue events.
Trials that are stopped early may systematically overestimate treatment effects and where the number of accrued outcome events is small, the overestimation may be very large [ 45, 46].
We would have also accrued fewer events, confirming that HbA1c ≥6.5% alone defines fewer persons as having diabetes than does the combination of FPG or 2hPG, as found in the National Health and Nutrition Examination Survey (10) and the Finnish Diabetes Prevention Study (7).
Owing to the low annual incidence of cancer, screening studies take a long time to accrue enough events to provide clear directions for implementation, and progress is slow.
First, the average event rate by intervention group is a measure of the average number of events accrued per person-time.
In 1961 and 1962 he won the PGA Order of Merit for the most points accrued during European events.
During the development phase, all except Onder et al 14 used a prospective case-cohort design method, where events accrued over the study period.
This observation, combined with the large number of patients exposed to linagliptin and the higher number of CV events accrued compared with previous analyses, therefore, supports the validity of the findings.
In the leukemia trial [ 9], multiple amendments, most notably amending the primary endpoint, were made subsequent to interim analysis with knowledge of treatment-arm specific rates in an apparent attempt to increase the number of events accrued and achieve a successful trial, but a substantial bias was introduced.
