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The large scale of the model and the implementation of posttranslational protein modifications allowed us to account for extensive crosstalk among signal transduction pathways.
While an embolus might account for extensive necrosis in the region supplied by the nutrient artery, this would be impossible in the regions supplied by the periosteal vessels since they are numerous and small.
If vaccine-induced immunity to HCV is to be antibody driven, a strong and broadly cross-reactive response is needed to account for extensive global diversity and inherent mutability of the virus [37-39] [37-39]
Because of the way supertrees summarise taxonomic congruence, they limit the impact of individual genes on the global topology and account for extensive differences in evolutionary rates and substitution patterns among genes in a gene-by-gene manner [ 16].
We believe that our approach is a practical and informative strategy for studying how the assignment of parameter values affects the ability of a complex reaction network to account for extensive data sets.
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As EMT accounts for extensive morbidity and varying therapeutic responses, several plausible targets and appealing regimens have emerged.
Nevertheless, a few of these compositions are very dominant accounting for extensive shares of land (see Fig. 6).
The instability of the ferryl could account for the extensive haem and protein damage and is in agreement with extensive protein radical formation on multiple free radical sites in the mutants as compared to the WT, resulting in unresolved singlet EPR signal.
Whether it's out of patriotism and love of country, or it's for economic reasons and increased opportunities, minorities (and the poor for that matter) join and account for an extensive proportion of our military.
This current stratification scheme fails to account for the extensive prognostic variability that exists between molecular subgroups.
Nevertheless, data indicate that this effect cannot be considered sufficient to fully account for the extensive differences.
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