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This method uses a graph permutation algorithm to create a null distribution that takes into account connectivity biases of the known interactome to identify genet sets with statistically enriched interactions between RNAi targeted gene products.
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We show that failure to take into account migratory connectivity may doom some regional populations to extinction, whereas including information on migratory connectivity results in the protection of the species across its entire range.
Without taking into account the connectivity in an underlying network, a large amount of network bandwidth can be consumed in forwarding packets.
For systems with complex geology, we show that measures of point values of permeability such as the median must account for connectivity within the reservoir before such measures may be used to reflect permeability.
Parameterizing SCR models in terms of one or more parameters that relate the resistance of the landscape to explicit covariates allows us to explicitly accommodate landscape structure and account for connectivity of the landscape simultaneous with modeling test of density.
These models were later also used in network simulations taking into account the connectivity between lobula plate cells of the horizontal (HS- and CH-cells; [53]) and of the vertical system [54].
The second method takes into account the connectivity in the network.
The hepShReD graph was also partitioned using Newman's metric [ 14], which only takes into account network connectivity.
To assess the validity of this finding, a "biased" randomisation strategy was employed that took into account the connectivity of the proteins within the essential sub-network.
The MCL algorithm can detect cluster structures in graphs by a mathematical bootstrapping procedure which takes into account the connectivity properties of the underlying network.
Indeed, by taking into account molecular connectivity between viruses and diseases, the Human Infectome-Diseasome Network generates new mechanistic hypothesis concerning their molecular relationships.
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