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Overall, the mathematical models that take into account cellular quiescence in tumor growth are based on earlier mathematical work.
A previous model studied the probability of treatment failure as a result of drug resistance, but did not take into account cellular quiescence [41].
This approach may take into account cellular factors required for viral replication and maturation or pathogenic processes.
This blood study is the first to reveal sex differences in DNA methylation by taking into account cellular heterogeneity of blood in the analysis.
To date, several genome-wide methylome studies have revealed sex-biased DNA methylation, yet no studies have investigated sex differences in DNA methylation by taking into account cellular heterogeneity.
After normalization, taking into account cellular viability and mRNA quantity used for the retrotranscription step, the mRNA half-life was determined by fitting mRNA quantity evolution by a decreased exponential (least square) method.
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Pihan, G. A. et al. Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression.
In our previous studies21,30,31,33, it has been revealed that PHE model is a powerful and potential model to simulate single cell mechanical behavior since it can account for cellular solid-fluid interaction.
An interpretation of the multi-exponential NMR signal of leaf tissue taking into account both cellular compartmentalization and heterogeneities at tissue level has been proposed on the bases of the NMR experiments, micrographs and physiological leaf characteristics.
Previous studies have demonstrated the sensitivity of the NMR signal to both cell and tissue modifications in oilseed rape leaves during senescence, and one interpretation has been proposed taking into account both cellular compartmentalization and heterogeneity at the tissue level.
This should be taken into account when cellular models are used for molecular and biochemical studies in McArdle's disease.
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