Accordingly, wild-type ataxin-1 can also form similar nuclear structures, and deletion of the self associating region prevents nuclear accumulation of polyQ-expanded ataxin-1 in COS cells and transgenic mice [3], [10].
Translation of the PiT1neo transcript would produce a non-functional PiT1 protein lacking exons 6 to 11 due to the presence of an in frame stop codon 65 bases downstream to exon 5. Accordingly, wild-type PiT1 mRNA levels are significantly reduced both in PiT1neo/+ and PiT1neo/neo embryoembryo (35% and 15% of the wild-type, respectively) (Fig. 1F).
Accordingly, the Wild West mentality was extended to Green Berets riding to victory on horseback and the Taliban perfectly cast with eye patches and black turbans being brought to justice. .
Accordingly, the wild type allele at CCR5 d32 conferred an OR of 1.39 (95% CI = 1.05 to 1.84) for developing RA.
Accordingly, both wild-type recombinant HGSNAT and polymorphic mutants almost completely co-localized with the lysosomal markers LysoTracker Red or LAMP-2 (representative data are shown in Figure 4).
Accordingly, in wild-type cells, most PrP∗ is maintained in a soluble state through its interaction with ER chaperones, whereas under acute ER stress conditions, when chaperone availability is limiting, PrP∗ can bind to Tmp21.
My mother would have used any rabbit caught by my grandpa, and the pie would have had more or less meat accordingly – so a wild rabbit of any size will do here.
Accordingly in the wild, C. rotundicauda scavenge on small fish, oligochaetes, small crabs and thin-shelled bivalves (Zhou and Morton 2004).
Accordingly, overexpression of wild-type MKK-7/JNK-1 in LRP-1 expressing control cells stimulated the accumulation of talin-containing peripheral adhesion structures (Fig. 9E vs 9C).
Accordingly, extracts from wild-type livers possessed a fraction of the PanK activity that was refractory to acetyl-CoA inhibition (Fig. 1C).
Accordingly, functional recombinant wild-type human Fas ligand extracellular domain (hFasLECD) and its derivatives have been produced in heterologous systems using several kinds of expression hosts including Escherichia coli[ 7], Pichia pastoris[ 8- 10] and Dictyostelium discoideum[ 7].
