Sentence examples for accordingly inhibiting from inspiring English sources

Accordingly, inhibiting this signaling axis by the use of specific small molecule inhibitors of JAK2 has recently been investigated as a point of therapeutic intervention in multiple human tumor indications [3], [21], [22], [23], [24].

The role of SSADH appears to primarily metabolise a toxic by-product of glutamate and GABA metabolism SSA and, accordingly inhibiting its activity would be anticipated to have deleterious effects.

Accordingly, inhibiting this pathway might lead to induce apoptosis.

Accordingly, inhibiting CDK4/6 in hPSCs with a small molecule increases G1 length while inducing endoderm differentiation.

Accordingly, inhibiting PI3P production using the small compound PI3K inhibitor LY294002 that inhibits the formation of WIPI-1 puncta, also reduced the abundance of CD11b, marking NB4 differentiation (Supplementary Figure 2).

Here we observed that Baicalin could reduce IL-6R and RORγt mRNA expression in spleens of MRL/lpr mice (Figure 4E), and Baicalin could accordingly inhibit TH17 cell differentiation in vivo (Figure 4F).

Results showed that OA still stimulated phosphorylation of ERK in Ad-GFP transfected VSMCs, however, when cells were transfected with Ad-PGC-1α, the phosphorylation of ERK decreased approximately 80% (p<0.001 versus Ad-GFP, Fig. 5B), which almost reverted the OA-induced phosphorylation of ERK, and accordingly inhibited OA-induced VSMC proliferation and migration.

The effect of miR-25 is shared by the other members of the miRNA family: miR-92a and miR-363 target MCU mRNA and reduce MCU protein levels and, accordingly, inhibit mitochondrial Ca2+ uptake, without affecting [Ca2+]c and [Ca2+]er (data not shown).

Accordingly, GnIH inhibits the development and maintenance of gonadotropin-dependent gonadal functions [16].

Accordingly, acadesine inhibited S6 phosphorylation, in agreement with the observed time-course of AMPK activation.

Accordingly, NAC inhibited Nrf2 nuclear translocation mediated by ATO (Supplementary Figure 1A).