Sentence examples for accordingly activated from inspiring English sources

Accordingly, activated PEDs S-alkylate critical cysteine residues on KEAP1 and HSP90, leading to activation of the transcription factors Nrf2 and HSF-1, respectively (Satoh et al., 2011; Zhang et al., 2011).

Accordingly, activated AMPK elicits pleiotropic effects including generally increased catabolism and decreased anabolism, improved endothelial function, reduced inflammation, or improved redox balance [ 12- 14].

Accordingly, activated pDCs, as a major source of IFNα, are possibly involved in the pathogenesis of SLE.

Accordingly, activated stellate cells respond by contraction to vasoactive substances.

Taken together, this is consistent with the inside-outside model, with cells using extent of cell contact or polarity (or a combination of both) to read-out their position in the embryo and accordingly activate or inactivate Yap-dependent Tead4 activity.

Our observations suggest that certain cancer cell lines, while they may have mesenchymal characteristics when they are cultured on rigid substrates, when placed in a soft microenvironment they may respond accordingly by activating an epithelial-type program.

Where this is not the case, the relevant programs can be compiled and added to the database LZM modules and activated accordingly.

In addition, a down-regulation of Cyp7a1, encoding the rate-limiting enzyme in the cholesterol-metabolizing bile acid synthesis pathway, was observed in these tumors and accordingly, tumors with activated MAPK signaling contained significantly higher levels of cholesterol [ 32, 33].

Accordingly, GP is activated allostericaly by AMP and also covalently via phosphorylation, the latter resulting from a signalling cascade that can be triggered by either Ca2+ or cAMP [ 13].

In the presence of sensory inputs, activity in the network shifts along the connectivity ring, in correspondence with movement of the head, and different sets of cells are activated accordingly.

Thus, the experimental design imposes that the animal is tested in a situation where the putative modulatory/peptidergic 'switch' is activated accordingly, and if 'the best' or any one of the best ligands is used, the result is a processing path in the brain that resembles a labeled line system.