The phrase "accompanied by a substantial decrease in" is correct and usable in written English.
It can be used when discussing a situation where one event or change occurs alongside a significant reduction in another variable or factor.
Example: "The new policy was implemented, accompanied by a substantial decrease in operational costs."
Alternatives: "alongside a significant reduction in" or "coupled with a considerable decline in".
Long time scale processes were observed to result in cation exchange properties accompanied by a substantial decrease in redox activity and/or CV currents of the polypyrrole electrode.
This was accompanied by a substantial decrease in the defect width (Figure 4C).
Consistent with previous observation [10], when Aurora-A was co-expressed with different amounts of Cdh1 in HEK293T cells, the increase in the protein level of Cdh1 was accompanied by a substantial decrease in the expression levels of Aurora-A.
Incubation was also accompanied by a substantial decrease in Vmax/KM.
We observed a slight (statistically significant) increase in the primary tumor pH with IEPA treatment, accompanied by a substantial decrease in necrotic tumor anatomy.
Incorrect conditioning induces a small amount of bias into the RB2 estimator but is accompanied by a substantial decrease in MSE.
We showed that the depletion of microparticles by ultracentrifugation from the VMR-CM and RANTES/CSLM0-CM was accompanied by a substantial decrease of S100A4 in CM as analyzed by Western blotting (Fig. 2C).
This can be rationalized by taking into account the similarity between the refractive indices of the thin AlOOH layer and that of the fused silica (Fig. 7B) so that the reflection of light from the resulting layered structure with n1 = 1.35 and n3 = 1.33 is accompanied by a substantial decrease of its intensity in agreement with the equation (1).
These structural distortions are accompanied by a substantial decrease of the relative mean-square displacements of the first ligands.
This loss is accompanied by a substantial reduction in desiccation resistance, as well as decreases in female courtship and copulation behavior by control males.
"In every site, introduction of the checklist had been accompanied by a substantial reduction in complications," he writes.
