Maintenance of biological databases consists of data conversions to accommodate site-specific data formats, and data submission to appropriate sites.
Project Accept [ 84] made an explicit programmatic point of allowing "site-specific adaptations" to accommodate "site-specific sociocultural differences" in its varying settings.
Clinicians argued for targets to accommodate site-specific pathways, and to take into consideration complexities in diagnosis and treatment, suggesting this was crucial for CRC, where diagnosis involved invasive and time-consuming procedures.
Likewise, Bayesian calculations of site-specific Ka/Ks using evolutionary models that accommodate codon usage differences [ 28], reveal a prevailing pattern of values significantly less than 1 (Fig. 5).
This approach is based on a site-specific rate model that accommodates excessive homoplasy and that utilizes secondary structure as a reference for proper alignment of rRNAs and tRNAs.
Tests of neutral evolution were carried out using both approximate methods (Codon-based Z test with Kumar model [ 27] that accommodates transition-transversion ratio bias) and Bayesian methods [ 28] of estimating site-specific Ka/Ks.
Detailed Bayesian analyses were conducted under the non-parametric CAT mixture model accounting for site-specific heterogeneity of the evolutionary process, and under RNA-specific doublet models accommodating the occurrence of compensatory substitutions in stem regions.
The method is universally applicable to a broad range of outcomes and designs, and it easily accommodates complex design features such as different follow-up plans, multiple treatment interventions, or different site-specific cluster effects.
The same analysis was repeated implementing the covariotide model of sequence evolution to account for heterotachy (changes in site-specific evolutionary rates across lineages) [ 59], which has been shown to effectively accommodate heterotachy [[ 66], but see [ 60]].
However, since UHS uses site-specific data and does not restrict its shape to any prescribed format, it has the flexibility to accommodate this feature by obtaining site-specific spectral ordinates from two sets of motion input (far-field and near-field data).
