Sentence examples for accommodated at the positions from inspiring English sources
Such highly packed system combined with the relatively limited space of the major groove causes stereochemical restrictions over the side chains that can be accommodated at the positions 153 and 157 in order to maintain the system interactions on their total integrity.
Despite being adjacent to AVR-PikDHis46, in the Pikp-HMA/AVR-PikD complex the side chains of AVR-PikDPro47 and AVR-PikDGly48 do not contact the same Pikp-HMA monomer and Ala/Asp residues could be accommodated at these positions without disrupting the Pikp-HMA/AVR-Pik interface.
This interaction is not present in the wild-type structure and suggests that the bulky hydrophobic valine residue cannot be accommodated at this position.
Close inspection of the Pikp-HMA/AVR-PikD interface reveals how a Glu could be accommodated at this position.
The complex structures reveal that the inhibitors are accommodated at the catalytic site with the glucopyranosyl moiety at approximately the same position as α-d-glucose and stabilize the T conformation of the 280s loop.
The conformational restriction of the proline at position 1835 leads to a small shift in the main-chain conformation but is otherwise well accommodated at the N-terminus of α3′.
This model assumes that the side groups are accommodated at interstitial positions within the crystalline phase owing to 2g1 kinks of the main chain.
Perhaps this is why only a few changes to M204 are tolerated [14] while it appears that several changes can be accommodated at positions of ETVr [6].
The isopropyl group of PP242 is too wide to be accommodated at a critical position in the channel in PI3KCγ (7), yet overall PP242 is the smallest compound and occupies the smallest portion of the pharmacophore space.
Though Rugova accommodated the U.S. position during negotiations at Rambouillet, he knew that Belgrade would never agree.
Before the university hired her in 1996, the chaplaincy position was called "Dean of Memorial Church"; in order to accommodate Karlin-Neumann, the position's name was changed to "Dean of Religious Life at Stanford".
