Results indicate that N-substitution on the piperazine ring can accommodate various substituted indole rings.
Where a substitution has been made, the hyperlink leads to an observable qualifier property combination to accommodate the substituted text, such that for the example above, 'resistance to cycloheximide: decreased' is linked to a list of all other mutant phenotypes incorporating decreased resistance to cycloheximide, as opposed to decreased 'resistance to chemicals'.
Recently, nNOS was found to accommodate phenolic substituted compounds in its active site, indicating that such substances could act as inhibitors of nNOS and also as antioxidants [ 43].
Residues near the C4 position are smaller in NPC1L1 (PHE35 and LEU216) compared to NPC1 (TRP27 and PHE203), increasing the size of the sterol binding pocket and accommodating C4 substituted sterols such as lanosterol.
Higher levels of inbreeding in the genotyped population can be accommodated by substituting "n" in the denominator of GN by the sum of (1 + F) across genotyped animals, where F are individual inbreeding coefficients derived from pedigree.
The drawback of their use is that the tunnel-shaped active sites of CBHs cannot accommodate the bulky substitutes, and the application of these substrates is limited with EGs.
In contrast, the distal aryl ring was more tolerant to functional group modifications and could accommodate a variety of substitutes at the C-2 or C-3 positions.
However, the modular design of PyCelegans can accommodate multi-animal tracking once an appropriate substitute for this function is implemented, without further changes.
OBJECTIVE: To describe the extent to which US physicians endorse substituted judgments in principle or accommodate them in practice.
The Imperial Japanese Army felt a smaller pistol of domestic design that could accommodate the standard 8×22mm Nambu cartridge was needed to substitute the larger, heavier, and only official military pistol, the Type 14 Nambu.
