Sentence examples for accessible to target from inspiring English sources

The lack of anti-trypsin activity by amblin is also surprising in view of the conservation of "canonical" reactive-site loops, and because our homology model suggests that the reactive-site loop of the N-terminal Kunitz domain remains accessible to target proteinases.

Rapid tests might be more effective in locations that are more easily accessible to target populations, such as shop front testing sites or even at home.

Because the imprinted sites in such an imprinting are situated at or close to the surface of MIPs, they are easily accessible to target protein molecules or cells.

Public health agencies need to know whether their messages are relevant for the recipient, reach the most appropriate and targeted groups at risk for injury or death, and are delivered through a modality and device accessible to target populations [ 4].

This strategy has the potential to overcome many of the transport barriers associated with targeting tumor cells in solid tumors, because the tumor vasculature is directly accessible to targeting vehicles in systemic circulation.

The endothelial cells in tumor vasculature are freely accessible to targeting molecules that are delivered intravenously [ 39, 40, 42 – 44 ].

In addition, the efficacy observed in vivo demonstrates that CD133 on the tumours is accessible to targeting using an ADC.

For preidentification of neurons with genetic layer IV characteristics which made them accessible to targeted electrophysiological recording, we crossed animals that expressed Cre-recombinase under a layer IV-specific promotor (Scnn1a) with our reeler strain and a suitable Cre reporter line (Madisen et al. 2010).

These kinds of data not only allow us to optimize future aptamer selections, but also clearly show that performances can be improved, while simultaneously consuming much less reagent, such as protein, making aptamer selections more accessible to targets that are difficult to purify or express in large quantities.

Five (1, 3, 5, 8, 9) out of the nine identified invariable regions had a high level of structure conservation between subtypes, suitable secondary structure and a significantly large solvent-accessible surface to target an anti-peptide/anti-viral response.

The additional properties of sortase A as an enzyme that is not required for Gram-positive bacterial growth or viability and is conveniently located on the cell membrane making it more accessible to inhibitor targeting, constitute additional reasons reinforcing the view that sortase A is an ideal target for anti-virulence drug development.