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This raises the question of whether p-EGFR can be accessible to downstream signalling components.
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Using several reporter assays, the authors show that when a premature termination codon (PTC) is present, the region of the ORF downstream becomes accessible to miRNA-mediated repression.
The nuclear receptor coactivator 2 (NCOA2) is a transcriptional coregulatory protein that acylates histones, which makes downstream DNA more accessible to transcription.
(The next spot downstream where the river is accessible to a motor vehicle is more than two hundred and sixty miles away).
Slightly downstream from Bauman Park are Vista Brook Park, about 4 acre with trails including one that is accessible to people with physical handicaps, a playground, and courts for basketball and tennis, and Fanno Creek Trail, about 2 acre, with picnic tables and trails.
When the module is in the KS state, the ACP-bound polyketide chain is also accessible to the individual ketoreductase, dehydratase, and/or enoylreductase domains as well as to the ketosynthase domain of the downstream module.
However, it is still unclear how phase information could be read out by distal downstream target cells, since the LFP at the soma of the pre-synaptic afferents is not directly accessible to remote neurons.
Fully accessible to wheelchairs.
All are accessible to hikers.
Not accessible to wheelchairs.
Most courses are accessible to all.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com