The phrase "accessible to activate" is not correct and may cause confusion in written English.
It could be used in contexts where you want to indicate that something can be easily accessed in order to activate it, but the phrasing is awkward.
Example: "The settings are accessible to activate the new features in the app."
Alternatives: "easy to activate" or "available for activation".
Cleavage at a site that releases the self-aggregation domain could render the membrane-attached MUC1* accessible to activating ligands.
Both Glu246 and Asp465 are geometrically accessible to act as general bases to activate Thr285, and the intermediates generated by proton transfer to Glu246 and Asp465 (1Zn-DE, 1Zn-D, Scheme S1, Supplementary Information) were isoenergetic within the limitations of the computational approach used (Supplementary Table S8), indicating that either residue may activate Thr285.
Our data now raise the distinct possibility that eating disorders such as anorexia nervosa may be caused in part by the "sub-normal" levels of circulating BDNF and the resultant failure to activate the peripherally accessible orexigenic TrkB axis.
Hearing what other students elaborate upon could also serve to activate or uncover the less accessible prior knowledge in the listeners.
In contrast, in the presence of the translocating βγ9 subunits, the tethered αq is able to activate PLCβ because it is accessible to PLCβ after βγ dissociation and translocation.
Because E2 continues to activate ERα, the AF2 site is still accessible and the compounds can bind the pocket and inhibit the receptor in TamR3 and TamR6 cells.
We focused our design on recognition of distance and geometry as the simplest parameters to achieve site selectivity, which has allowed us to activate CH bonds at remote sites that are previously not accessible.
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A biopsy test that quantifies the amount of MUC1* that is accessible to its activating ligands would be a more accurate prognostic indicator than tests that detect portions of MUC1 that are typically shed from the surface of tumor cells.
Thus, an auto-inhibited kinesin molecule would not be expected to be accessible for TRAK binding or available for transport, whereas binding to a TRAK adaptor would be expected to activate kinesin motility.
