Sentence examples for accessible on the cell from inspiring English sources

Synaptotagmin-1 becomes accessible on the cell surface after synaptic vesicle exocytosis and can be labelled with an antibody, which is then internalized when the vesicles are retrieved [43].

Nucleosomes become accessible on the cell surface, exposing negatively charged nucleic acid containing complexes.

These studies found that despite the presence of accessible carbohydrates on the cell surface of S. cerevisiae SP-A does not bind to this yeast [20], [21].

To date, erbB2 directed therapies have largely focused around the use of immunoreagents, because erbB2 is accessible on the cancer cell surface.

The mutant S1 and S3 full-length PrP, as well as the C2 fragment, was found to be accessible on the surface of cells, and the mutants were internalized with similar kinetics to a WT PrP control.

Certain normal epithelial tissues and embryonic stem cells express EpCAM [24] [26], but there is evidence to suggest that EpCAM on normal epithelial tissues is largely sequestered while it is accessible on the surface of cancer cells [27], [28].

There is also evidence that membrane-associated α-actinin is accessible on the surface of mesangial cells [ 15, 18], and the increased glomerular α-actinin expression after epithelial podocyte confluence and the occurrence of proteinuria suggest a role for α-actinin in renal pathophysiology [ 32, 33].

In addition, the presence of TACSTD2 on the cell surface makes it more accessible to antibody-based therapeutics.

They knew they'd found a promising drug target because GRP78 is expressed on the cell surface, where it's easily accessible to drugs.

LAMP-2 is also present on the cell membrane, however, and is immediately accessible to circulating auto anti bodies [ 94].

These features and properties have been used in combination to find genes that are exposed on the cell surface and could therefore be accessible to the immune system.