The degree of functionality gives the total number of accessible regions in the sequence that may promote an interaction with another RNA molecule.
Gene-specific primers used in the present study (Table 2) were designed using the sequences accessible in the NCBI Reference Sequence and the software Primer Premier 5.0.
We have developed TAB 004, a monoclonal antibody highly specific to a protein sequence accessible in the tumor form of MUC1 (tMUC1).
Genome sequencing efforts for Listeria have, so far, largely focused on L. monocytogenes; as of August 15, 2010, 25 L. monocytogenes genome sequences are publicly accessible in standard sequence databases (GenBank; EMBL).
The Macaca fascicularis 43RCA-H and 43RCA-L sequences (VH and VL domain sequences, respectively) are accessible in the data banks under the accession numbers [EMBL: FJ178346 and EMBL: FJ178347].
This may be also caused by the low number of relevant CoHV-1 sequences accessible in the GenBank database.
We also tested a modified energy score that weights the accessibility against the hybridization energy with factor α: where Ehybrid denotes the hybridization energy of the interaction and ED x denotes the energy required to make the interaction site accessible in sequence x.
This effect may have been caused by a pyrophosphatase activity which eliminates the pyrophosphate from the 5'-end of primary transcripts making these transcripts accessible for the sequencing procedure followed in the processed transcript-enriched sample.
The data were deposited in the Campylobacter Internet-accessible database, enabling the sequence types (STs) of the isolates to be established (http://campylobacter.mlst.net/).net/
In all likeliness, genomic sequencing will continue to become more accessible in the future, and will help cast light on how biodiversity is generated and maintained.
