Sentence examples for accessibility to downstream from inspiring English sources

The increased signaling strength of CRAC channels confined to ER-PM junctions was not a consequence of greater accessibility to downstream signals such as Syk, the tyrosine kinase that activates c- fos through phosphorylation of STAT5, because resting Orai1 channels, activated Orai1 channels, and the constitutive V102C-Orai1 channel mutant all co-immunoprecipitated with the kinase.

Specificity can be achieved by compartmentalisation, where the accessibility to upstream activators and downstream substrates is regulated by subcellular localisation.

We propose that it controls the phosphorylation status of the downstream Rnt1 cleavage product and thereby regulates its accessibility to the torpedo Rat1.

Handicapped accessibility to the park was improved.

While there are Web Content Accessibility Guidelines, Lyons wants web accessibility to be more strongly enforced.

And, he said, accessibility to design must improve.

An accessibility to one's own self-deprecation.

A big challenge is accessibility to basically everywhere.