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However, only 33 PKs were cleaved by CASP3; therefore, to be cleaved by CASP3, the DXXDX sequence and a structural element –probably accessibility – are required.
Since the accessibility relation is required to be reflexive, \({\mathcal{M},\Gamma{\Vdash}X}\).
However, the D-loop contains a junction at both duplex ends and we found that accessibility of both junctions is required for optimal D-loop disruption by WRN, suggesting that WRN engages both junctions (Fig. 7).
Provision for easy accessibility of archived datasets is required.
The function of Snail1 could alternatively be modulated by its subcellular localization so that nuclear translocation of cytosolic Snail1 is required for accessibility of target promoters [30], [31].
The most probable explanation for this observation is that in addition to other factors such as the localization of the protein, the adoption of an appropriate conformation and solvent accessibility of this tri-peptide is required for the glycosylation reaction [14,15].
Previous research has clearly demonstrated that enzymatic digestibility of pretreated biomass is directly related to cellulase accessibility, indicating a minimal average cell wall pore diameter of 51 Å is required for enzyme accessibility and significant activity [ 42].
While we found that DNA methylation is required for low accessibility of several tested loci, DNA methylation was reported to be only partially required for formation of heterochromatic chromocenters19.
An S4-model is defined as a T-model except that it is required that the accessibility relation be transitive i.e., that, where w1, w2, and w3 are any worlds in W, if w1 is accessible to w2 and w2 is accessible to w3, then w1 is accessible to w3.
This mobile diabetes retinal screening program visits individual general practitioner practices and appears to provide sufficient accessibility in general, but further improvement is required in trying to reach patients living in socially deprived areas.
These results indicate that cytosine methylation is required to reduce the accessibility of long genes and TE genes.
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