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1, 128, 135 Nevertheless, HAT mainly affects remote rural communities where the health infrastructure is basic; furthermore, there are other endemic areas where accessibility is complicated because of security problems or topography constraints.
For subterranean species oxygen accessibility is complicated by the water saturated atmosphere in the cave and the increased permeability of their integument, which may blur the distinction between aquatic and terrestrial habits (as in some species of "amphibious" Leptodirini, e.g. [ 45, 46]).
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Experiments intended to determine the effects of pH on metal accessibility were complicated by protonation of the probe ion, fluoride, at a pH close to that of the leachate solutions (the pKa of hydrofluoric acid is 3.20).
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