Sentence examples for access of substrate from inspiring English sources

Therefore the I148M substitution possibly blocks access of substrate to the catalytic site (Huang et al., 2011).

This can be due to the fact that the zeolite particles could slow down the access of substrate to the enzyme within the biomembrane, and thus, the diffusion limitations become significant.

Permeabilization by a toluene treatment (at 1 % v/v) was frequently employed in bioconversion to guarantee access of substrate and cofactor into the cells (Cánovas et al. 2005; Zhang et al. 2009).

P-glycoprotein played an important role in restricting access of substrate drugs across the BBB in to brain [33], [34].

Many lipases exhibit a mobile subdomain called lid, which controls the access of substrate molecules to the catalytic center.

The inhibitor I29 domain is also found at the N terminus of a variety of peptidase precursors where it forms an alpha-helical domain that runs through the substrate-binding site, preventing access of substrate.

A large funnel allows access of substrates to the active-site; another cavity, accessible to the solvent, is also present between the two monomers; this second cavity could allow the entrance of molecular oxygen necessary for the oxidative reaction.

This prevents access of substrates to the active site.

Control of biochemical reactions in living cells is based on the principle of compartmentalization, whereby the access of substrates to the active sites of enzymes is regulated by the structure of organelles with semi-permeable membranes.

They seem to modulate the access of substrates to the prosthetic group at the distal side as well as the flexibility and character of the bond between the proximal histidine and the ferric iron.

The outer two rings in the stack consist of seven α subunits each, which serve as docking domains for the regulatory particles and the alpha subunits N-termini form a gate that blocks unregulated access of substrates to the interior cavity.