For example, the lack of patient acceptance of random allocation and receiving controlled treatment may be one of the major factors, especially in China.
The whole process of acceptance, storage, allocation, use, counting and recovery of the trial drug are monitored by the CRA, Ethics Committee and Quality Control Committee, so as to ensure the safety and stability of the trial drugs.
These steps also required collaboration with the management staff of the health and social services centre (CSSS) to ensure acceptance of the changes and allocation of resources.
At the same time, it is of great importance for the acceptance of such policy measures that questions regarding allocation, in particular, between renters and property owners, as well as incentive problems [[46],[47]] be given full consideration [[48],[49]].
Apparently, the quality of evidence "can be assessed based on the source type (from meta-analyses and systematic reviews of triple-blind randomised placebo-based clinical trials with concealment of allocation and no attrition at the top end, down to conventional wisdom at the bottom), as well as other factors including statistical validity, clinical relevance, currency, and peer-review acceptance".
Concealment of allocation.
Method of allocation concealment.
Examining individual cases this reflected the initial acceptance of both kidneys by one institution followed by a secondary allocation occurring when the first centre was unable to proceed with both transplants.
While we would expect an analysis that ignores our allocation method to be conservative and lose some power, developing specific mechanisms to account for the baseline covariate balancing (resulting from our allocation method) would be critical to "facilitate acceptance of trial results and minimize potential for controversial interpretations" [ 61].
