Exact(21)
However, to allow for dosing variations when using a fixed dose combination and the inter-subject pharmacokinetic variability seen with artesunate, the decision matrix selected the dose above that which showed, on average, acceptable efficacy.
Educational interventions showed an acceptable efficacy.
CBA has an acceptable efficacy profile in real practice.
Additional work is needed in this area to define agro-ecosystems where dry soil may be solarized with acceptable efficacy.
Salvage prostate cryotherapy is a viable option with an acceptable efficacy and toxicity profile.
Salvage prostate cryoablation (SPC) has an acceptable efficacy and toxicity profile (Ahmad et al, 2013).
Similar(39)
However, all validating systems still resulted in acceptable predictive efficacy, with accuracy factor 1.00 1.26.
Consequently, these compounds may need to be given at higher doses or as multiple administrations in order to provide adequate therapeutic concentrations to give an acceptable anthelmintic efficacy [ 3– 5].
Whilst this significant loss to follow up is not ideal and would not be considered acceptable in efficacy trials, as a population- wide intervention with a greater degree of external validity the experience of the GHS highlights the complexities of undertaking such an evaluation, and the constant tension between scientific rigour and implementation research in the real world.
This guidance recognizes that although improved long-term glycemic control measured by HbA1c leads to reduced risk of microvascular complications and remains an acceptable primary efficacy endpoint, T2DM is also associated with increased risk of CV disease--the primary cause of morbidity and mortality in T2DM patients.
Items assessed willingness to pay (continuous), minimum acceptable vaccine efficacy (ordinal in increments of 10%), and whether cash incentives, dosing (multiple vs. single), administration (oral vs. injected), and/or vaccine-induced positive results on future HIV tests would affect vaccine acceptability.
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