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The phrase "accept major changes" is correct and usable in written English.
You can use it when discussing the willingness to embrace significant modifications or alterations in a situation, project, or plan.
Example: "In order to improve our workflow, we must be ready to accept major changes to our current processes."
Alternatives: "embrace significant changes" or "welcome substantial changes."
Exact(7)
But President Obama seems unlikely to accept major changes in the agency, administration officials said.
The issues facing the schools are so complicated, it is almost impossible to get a roomful of people to accept major changes, at least not without bruising debates.
These constraints are pressing the military to accept major changes in the way it operates, especially as it tries to end long-running wars in Iraq and Afghanistan.
Stuart M. Butler, a vice president of the conservative Heritage Foundation, said Mr. Clinton had persuaded Congress to accept major changes in health and domestic policy by pursuing an incremental approach.
Hunt and NHS Employers, which represents hospitals and others NHS care providers, want junior doctors to accept major changes to their terms and conditions to help create the seven-day NHS that David Cameron has pledged to introduce by 2020.
Heyns, a South African law professor, told the meeting: "Are we to accept major changes to the international legal system which has been in existence since world war two and survived nuclear threats?" Some states, he added, "find targeted killings immensely attractive.
Similar(53)
She said she accepted major changes have to happen but she wants the Department of Health to explain why it wants to close the Belfast City Hospital unit.
All accept major credit cards.
She decided that she would not accept unless major changes were made in the pageant to show the horrors of slavery and acknowledge the Confederate defeat.
Although it is generally accepted that major changes in the earth's history are significant drivers of phylogenetic diversification and extinction, such episodes may also have long-lasting effects on genomic architecture.
Assuming that clinicians agree with, and accept these recommendations, major changes in practice are often required.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com