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One can argue that when tau loses its ability to bind to MTs, it interacts with Aβ to form a more stable oligomer, accelerating aggregation.
In fact, experiments by Textor et al. (2006a) indicated that acid solutions (i.e., mixtures of water and soluble gases like SO2, H2S, HCl, and HBr), or soluble salts, coating particles, are able to lower the freezing point of ice, increasing the mass of liquid water, accelerating aggregation processes, due to an increase in liquid water availability (Textor et al. 2006b).
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Furthermore, direct injection of protein aggregates can induce or at least accelerate aggregation of homologous proteins in animal models of amyloid diseases (Lundmark et al., 2002; Meyer-Luehmann et al., 2006; Clavaguera et al., 2009; Eisele et al., 2010; Luk et al., 2012; Morales et al., 2012).
To improve the selectivity of the reaction and accelerate aggregation of AuNPs, NaCl (final concentration of 0.1 M) was added to the mixture.
It was suggested that strong coordination strength of Eu III) decreases zeta potential, thereby accelerates aggregation of NCs, and favors the transformation process from NCs to NRs.
In the design fields, professional projects should encourage an integrative transdiciplinary process, rather than devolving into arcs of accelerated aggregation of technologies.
It might be expected, therefore, that the increased integrin activation would accelerate aggregation.
If this is the case, accelerated aggregation, depleting oligomeric ataxin-1 species, may be cytoprotective.
Doing so would increase the cell collision rate and thus accelerate aggregation.
We established a mathematical model that successfully predicts long-term aggregation data based on accelerated aggregation experiments [32].
Addition of salts to samples containing proteins denatured at low pH is known to accelerate aggregation dramatically [30], [31].
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