Sentence examples for accelerated unfolding from inspiring English sources

In this example we also observed a diminished slope for ln kU vs 1/ T. The destabilization of the fold associated with the [P12W] mutation predominantly results from accelerated unfolding particularly at the lower temperatures.

This was confirmed by accelerated thermal unfolding in all variants, as well as decreased proteolytic stability and accelerated thermal inactivation in most variants.

These relationships are useful for predicting trends, e.g. how a change in solvent will change the rate of a chemical reaction, or how a mechanical pulling force will accelerate the unfolding of a protein.

Temperature is often used to accelerate protein unfolding and it has been shown that this does not affect the protein unfolding pathway (Day et al., 2002).

Moreover, determination of TTR thermodynamic and kinetic stabilities are typically established using chaotropes such as urea, GndCl, or GndSCN to accelerate protein unfolding rates on convenient laboratory time scales.

It was literally a minute by minute unfolding, accelerated and complexified by millions of online activists and commentators, who could shape and reshape conventional wisdom in a matter of moments.

In addition to the marked left-shift of the curve, Y133H revealed a steeper slope of the curve indicating an accelerated progress of unfolding with complete denaturation at 46°C.

Our single-molecule atomic force microscopy results reveal that loop elongation decreases the mechanical stability of GB1 and accelerates the mechanical unfolding kinetics.

Thermal unfolding was accelerated with a shift of the transition midpoint (wild-type, 52.6°C) by >4°C in most variants and down to 40°C in variant R181C.

Whilst cis trans isomerisation does result in bond lengthening, the authors suggest that force induced unfolding accelerates this isomerisation, rather than force driving isomerisation per se [ 38 ].

These experiments could not distinguish whether binding of telomerase accelerates G-quadruplex unfolding during replication or whether a telomerase-associated G-quadruplex-specific helicase might be actively involved in this process.