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Changes in land use and intensification of agricultural pressure have greatly accelerated the alteration of the landscape in most developed countries.
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At this transition, the HapR-Qrr feedback provides a surge in qrr transcription, which accelerates the alterations in gene expression required for the V. cholerae LCD lifestyle.
The emergence of next generation sequencing technologies has rapidly accelerated the discovery of somatic alterations in cancer genes, by exploiting greater depth-of-coverage to increase the sensitivity of detection within low purity samples [ 13, 16- 22].
In some cases these alterations clearly accelerated the licensing of palliative drugs and made effective treatments available to people who had previously been denied access to them.
The discovery of somatic sequence alterations, has accelerated the investigation of ir underlying mechanisms in carcinogenesis.
The addition of 60% fat from cocoa butter in the HChCh diet accelerated the development of these histopathological alterations within 12 weeks.
Globalisation accelerated the branding process.
They can be subject to genetic alteration, associating with tumourigenesis for inherited (for example, BRCA proteins) and for sporadic (for example, Aurora A: 30% to 60% overexpression) breast cancer because they cause genetic instability that may permit secondary alteration, accelerating the development of cancer.
Advances in sequencing technology will certainly accelerate the characterization of somatic alterations in the cancer genome, but the task of defining the importance of observed somatic changes will continue to rest on the shoulders of future laboratory investigators.
DNA damage response pathways are frequently mutated in individuals with inherited forms of cancer predisposition, and there is ample evidence that these changes accelerate the accumulation of genetic alterations that drive tumour-cell development.
Essentially, the same neurodegenerative disease can be driven in a relatively young person by a genetic alteration that accelerates the induction of the proteinopathy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com