Such a phenomenon may be crucial during aging or in the initial steps of leukemia, where clonal dominance may uniquely arise as a consequence of the accelerated duration of G0 exit of LT-HSCs.
This indicates that c-Myc overexpression accelerates the duration of S-phase by ∼40% in normal human fibroblasts.
To examine the long-term effect of exclusively accelerating the duration of exit from quiescence upon reception of mitogenic stimuli, we enforced CDK6 expression in LT-HSCs in vivo, where HSCs return to G0 after most divisions under homeostatic conditions (Wilson et al., 2008 and Figure S1B).
Furthermore, no accelerated corrosion for duration of 3000 h at below 1173 K was first demonstrated.
For the comparator cohorts, monthly transition probabilities were calculated from the median durations of accelerated phase and blast crisis (Kolibaba and Druker, 2000; Reese et al, 2000).
Drivers' reaction times to a pedestrian in the zebra crossing were modelled using a parametric accelerated failure time (AFT) duration model with a Weibull distribution.
Following the gross analysis, absorption rate was accelerated with increased implant duration and decreased thickness.
This time course provides the opportunity to build up a range of different mutations and sub-clones, with blast crisis usually preceded by an accelerated phase of variable duration, suggesting a multi-step pathogenesis.
The duration of the accelerated field test played an important role in the steel performance rating.
It has been found that applying vibrations for different duration per day accelerated tooth movements between 15% and 30% in animal experiments [35, 44].
For (vartheta_{1}in(a_{1},vartheta_{ast})) (or (vartheta_{1}in (vartheta_{ast},a_{1})) depending on the case), the cumulated duration of the accelerated phases does not depend on (vartheta_{1}) (in particular because the last rapid phase stops when the coordinate reaches (n+a_{1})).
