The phrase "accelerated dose of" is correct and usable in written English.
It can be used in contexts related to medicine, pharmacology, or treatments where a dose is administered more quickly than usual.
Example: "The patient received an accelerated dose of the medication to manage the acute symptoms more effectively."
Alternatives: "increased dosage of" or "rapid dose of".
The second stage of the study used an accelerated dose titration schedule involving treatment of cohorts of one to six patients (Simon et al, 1997).
Furthermore, when isolated primary muscles fibers are exposed to extracellular HMGB1 in vitro, the fibers begin expressing MHC class I antigens on their surface and demonstrate an accelerated, dose-dependent efflux of calcium ions [ 17], suggesting a role for HMGB1 in the perpetuation of inflammation and muscle fiber degeneration even in the absence of infiltrating lymphocytes.
For higher dose levels, this was after at least one patient had completed 4 weeks of treatment; during this accelerated dose-escalation phase, the majority of toxicities above grade 1 in severity developed after the decision to dose escalate had been taken.
For all patients: − an accelerated dose-schedule in the final week of RT onwards will be simulated, delivering 1.8Gy bi-daily to an isotoxic dose satisfying original Organ at Risk (OAR) constraints.
Alternative strategies for vaccination with RV1 and RV5 were considered, including: administration of vaccine doses consistent with ACIP recommendations ("Base Case" schedule), accelerating the 1st dose of vaccine only, and accelerating the 1st and subsequent doses of vaccine.
More recently, the development of intensity-modulated radiation therapy (IMRT) has led to the integration of accelerated fractionation, dose escalation, and concurrent chemotherapy in the treatment of BOT SCC 15– 15.
Accelerated (dose-dense) chemotherapy, in which the frequency of administration is increased without changing total dose or duration, may increase the efficacy of cancer chemotherapy.
Due to accelerated repopulation, higher doses of radiation or accelerated radiotherapy (or radiation given over shorter total time) may be required to achieve tumour control (Withers et al, 1988; Maciejewski et al, 1989).
The impact of accelerating the 1st dose of RV vaccine was evaluated in a recent modeling exercise by Halvorson and colleagues.
In the present study we examined neurobehavioral effects of TCVs using both an accelerated vaccine primate schedule and the recommended pediatric schedule, neither of which appeared to affect neurobehavioral outcomes, thus suggesting that the toxicokinetics of EtHg in infant primates is not a limiting factor when using an accelerated schedule of dosing.
