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For decades, businesses have bought up teams as a way to add capabilities and accelerate entry into strategic and growing markets, according to Brad Wertz, President of interactive agency Rosetta.
According to Mr. Wertz, acquisitions of teams are typical to accelerate entry into new markets where the target company contains people with talent and experience in the desired sector.
Elevated T-SCEs has also been shown recently to accelerate entry into replicative senescence [ 26].
A three-year track also could allow students pursuing lengthy specialty residencies to accelerate entry into their chosen specialty field.
Up to a point, increasing the positive charge would increase the level of electrostatic attraction and thus accelerate entry of the substrate protein into the pore and strengthen the interaction with the Phe clamp region.
Thus a phage with this entry mutation would accelerate entry of the ectopic gene 1 to just 160 sec after entry of A1-A3, nearly 3 min faster than under host RNAP control.
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c-Myc shortens the duration of S-phase, which is different from the previous notion of c-Myc causing accelerated entry into S, through simultaneous activation of G1 cyclins [38].
LMW cycE isoforms function in the same manner as the full length proteins, and show increased binding efficiency to its partner kinase CDK2, leading to accelerated entry to S phase and genomic instability [35], [36].
The latter pathway was established by showing that brief low pH treatment accelerated entry through the plasma membrane by mimicking the pH of endosomes and by preventing endosomal acidification with inhibitors [11].
Consistent with the notion that phosphorylation-dependent activation of Cdc25s is part of the central positive feedback amplification loop that increases Cdk1/cyclin B activity and promotes entry into mitosis, ablation of Cdc25A and B delays G2/M transition [8] [10], whereas overexpression induces premature activation of Cdk1 and accelerates entry into mitosis [8], [10] [11].
This accelerated entry into the cell cycle appeared to be abortive, initiating an apoptotic response.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com