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Furthermore, direct injection of protein aggregates can induce or at least accelerate aggregation of homologous proteins in animal models of amyloid diseases (Lundmark et al., 2002; Meyer-Luehmann et al., 2006; Clavaguera et al., 2009; Eisele et al., 2010; Luk et al., 2012; Morales et al., 2012).
To improve the selectivity of the reaction and accelerate aggregation of AuNPs, NaCl (final concentration of 0.1 M) was added to the mixture.
It might be expected, therefore, that the increased integrin activation would accelerate aggregation.
Doing so would increase the cell collision rate and thus accelerate aggregation.
Addition of salts to samples containing proteins denatured at low pH is known to accelerate aggregation dramatically [30], [31].
Recent work [6] has suggested that fusion tags can act as templates for the aggregation of polyQ repeats, with expanded repeats acting to accelerate aggregation.
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It was suggested that strong coordination strength of Eu III) decreases zeta potential, thereby accelerates aggregation of NCs, and favors the transformation process from NCs to NRs.
In the design fields, professional projects should encourage an integrative transdiciplinary process, rather than devolving into arcs of accelerated aggregation of technologies.
If this is the case, accelerated aggregation, depleting oligomeric ataxin-1 species, may be cytoprotective.
We established a mathematical model that successfully predicts long-term aggregation data based on accelerated aggregation experiments [32].
The model also indicates that the aggregation process can start even before any proteasome inhibition is present, but that proteasome inhibition greatly accelerates aggregation progression.
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