Exact(4)
At first, these chemicals of abuse produce an intense pleasurable reaction, but ultimately, they flood the receptors of the cells to which they attach, and in the process, destroy them.
Dopamine has been widely implicated as the central mechanism through which drugs of abuse produce their effects [31].
If these drugs of abuse produce addictive behavior through VTA LTP, co-administration of cannabinoid and one of these drugs of abuse may neutralize their opposite effects on VTA synaptic plasticity and thereby block their individual addictive behavior during the development stage of drug addiction.
In animal models, acute withdrawal and protracted abstinence from alcohol and all other major drugs of abuse produce anxiety-like responses that are mediated by CRF and can be reversed by agents that block or reverse the actions of CRF (i.e., CRF receptor antagonists) (for review, see Heilig and Koob 2007).
Similar(56)
His abuse produced a young child, whom she has been raising alone for years.
The other was an examination of the causes and context of the abuse, produced by a lay review board.
One report said a police chief refused to file charges "as long as the abuse produced no marks".
Doctors, other health care providers and law enforcement officials say prescription drug abuse produces the same problems as street drugs: addiction, crime and broken families.
Calderon, a superb poet with deep psychological insights, explored astonishingly modern concerns: an intellectual elite manipulating nature, determinism undermining free will, child abuse producing criminality, men subjugating women.
Primarily, though, it is the representation of torture — and, more important, the assertion that such abuse produced information that led to Bin Laden — that has provoked outrage in some quarters.
Cocaine addiction, as with other stimulant abuse, produces psychotic symptoms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com