LOX-1 is highly expressed in blood-vessel-abundant tissues such as placenta, lung, marrow, and spinal cord, is moderately expressed in hippocampi, testicle, and large arteries, and is slightly expressed in heart, skeleton muscle, and ovary [ 19].
The occurrence of non-sink dissolution conditions following intravenous administration would result in a slower dissolution rate that would not be considered 'instantaneous.' Our data are consistent with slowly dissolving nanoparticles being taken up into organs by phagocytic cells of the mononuclear phagocyte system that are abundant in tissues such as the liver and spleen [38, 39].
Second, the amphioxus lymphocyte-like cells are abundant in tissues such as gut (data not shown) and gills, the first defense line against the foreign pathogens in amphioxus.
It is the major component of elastic fibres, particularly abundant in tissues such as arteries and lung, and also present in skin, breast, cartilage and some ligaments.
In potato, where only one isoform has been reported, UGPase activity was abundant in sink tissues, such as stems and tubers [ 16].
Some of the miRNAs were very abundant in certain tissues such as members of the miR167 family and gma-1512c, werehighly highly prevalent in the seed coats from multiple samples.
Therefore, it was rational to derive HMEC for these experiments from abundant and easily accessible tissues such is subcutaneous fat.
CYP1B1 expression has been shown to be abundant in hormone-dependent tissues such as uterus, ovary and breast (Tsuchiya et al, 2005).
PPARα is abundant in metabolically active tissues, such as the heart, and we observed DEHP-induced modifications to a number of PPARα target genes.
The acetylation level of K19 and K24 on histone H3 correlates with transcriptional activity, and intriguingly, these particular sites are most abundant in the lymphoid tissues, such as thymus and spleen, that primarily consist of dividing cells with active cell-cycle machinery.
Collagen I is the most abundant structural protein of connective tissues such as skin, bone, and tendon.
