Sentence examples for abundant strands from inspiring English sources

In the case of alphaviruses, the increased sensitivity of assays incorporating DNA hydrolysis probes should be useful, particularly when quantifying much less abundant strands.

Because imbalances in the synthesis of genomic RNAs and their full-length complements are common during RNA virus infections, false priming of the more abundant strand during the RT step of the assay is likely to inhibit accurate quantification of the less abundant strand, when standard unmodified virus-specific primers are used for reverse transcription and qPCR.

Thus we reject the hypotheses that a) the selection of the more abundant strand (5p vs. 3p) may shift and b) the stability of all miRNAs are coordinately regulated over pubertal testicular development.

The most abundant strand, therefore considered as the miRNA, should have no more than 4 mismatches with its corresponding miRNA* (especially within the duplex), including a maximum of 1 asymmetrical bulge of 1 or 2 nucleotides.

For example, pathways that bypass Drosha (figure 1) or Dicer processing have been identified 6 and a number of studies have shown a functional role for the less abundant (passenger) strands of some miRNA duplexes.

In the absence of coding properties, polarity is assigned conventionally to the most abundant viroid strand accumulating in vivo.

The potential significance of results in Table 2 is that 'orphan' Arabidopsis genes predicted by gene-finding algorithms and having relatively abundant antisense strand expression may actually be ncRNA genes.

In contrast, the most abundant preferred strand of mir-33 exhibited sequence divergence in the seed region.

This raises the possibility that the abundant passenger strand of miR827 may also be incorporated into the miRISC and hence stabilized.

Pyrosequencing data representing the mito-transcriptome poly (A) fraction in Atlantic cod identified an abundant H-strand specific long noncoding RNA of about 375 nt.

The most abundant sense strand-produced sRNAs were produced at the 5'D7 position, similar to the pattern observed in Arabidopsis, suggesting that the tasiRNA biogenesis pathway is highly conserved between plant species.