Sentence examples for abundant somatic mutations from inspiring English sources

These effects should be clear-cut and insensitive to the source of the sample (with the exception of certain tumors, where DNA may contain abundant somatic mutations).

Pediatric HGG is characterized by abundant somatic coding mutations, suggestive of defects in DNA damage repair (Jones and Baker 2014).

The lymphoma cells were found to have somatic mutations in class I and II HLAs with abundant CD4 and CD8 T-cell infiltration, which implies that the HLA mutations facilitate antigen recognition by T cells.

catalogue of somatic mutations in cancer.

Four hundred twenty-six genes had recurrent somatic mutations.

Genomic mutations could be divided into germline mutations and somatic mutations.

Traditionally, somatic mutations are detected by examining DNA sequence.

The majority of AML, however, is driven by somatic mutations.

Importantly, the somatic mutation signature in tumors with one germline and one somatic risk allele was indistinguishable from those with purely somatic mutations.

In the Catalogue of Somatic Mutation in Cancer (COSMIC) database, 101 non-synonymous LATS1 somatic mutations have been identified from 9183 unique human tumor samples (Fig. 1A).

NSCLC is a heterogeneous disease marked with a high rate of somatic mutations.