In addition, an abundant localization of the α1 subunit in the dentate gyrus was similarly demonstrated by immunocytochemical studies [ 39, 40].
aScoring scale: 0 = no localization; 1 = very slight localization; 2 = modest localization; 3 = abundant localisation.
aScoring scale: 1 = very slight localization; 2 = modest localisation; 3 = abundant localisation.
Fig. 4A shows abundant membrane localization of WT-ACE in lightly fixed-non-permeabilized cells, whereas we did not observe membrane localization of mutant Q1069R-ACE under the same conditions and detector settings (Fig. 4D).
In the presence of F. nucleatum, T. forsythia synergistically forms robust biofilms via cell-cell contacts in vitro [29] as is reflected in their prominent and abundant co-localization of both species along the entire length of the biofilm.
Similar to previous reports for mammalian VCP, we observed abundant VCP localization in and around the nucleus and diffusely in the cytoplasm.
Thus, abundant nuclear localization, and therefore the capacity to exert regulatory control over chemokine and cytokine expression, is likely a feature of oncogenic transformation in skin keratinocytes.
Very recently it has been described that absence of tuberin leads to abundant nuclear localization of EGFR in rat uterine leiomyoma-derived and LAM patient-derived cells [ 27].
We also observed abundant co-localization of GFP-tagged Arf79F with the LD marker CGI-58 on LDs, and the signal was distinct from signals marking the Golgi apparatus.
