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Thus, the disarming mechanism acts on relatively low abundance expression of cytosolic ectopic Smac.
Furthermore, according to mRNA abundance, expression of the gene encoding the MsmR regulator in the FCT-3 strain [23], [24] was enhanced under acidic conditions, while no pH effect was detected for the Nra FCT-3 regulator gene.
As a large number of genes fall into this class of low abundance expression [10], this lack of sensitivity potentially compromises current efforts to gain a complete picture of molecular pathways underlying GBM.
The relationship between mRNA abundance (expression level) and protocol is only weak and does not hold for each gene individually.
Polymorphisms located in introns can be "causative" if affecting transcript abundance (expression and stability) of genes [ 68].
To test our hypothesis, we make comparisons of abundance expression level and comparisons of expression level ratios.
Similar(40)
In contrast to microarrays, SAGE estimates the abundances (expression levels) of thousands of transcripts without prior knowledge of the transcripts being expressed.
However, many such predictions are not realized for different reasons, including absent or low-abundance expression of the miRNA in the cell, the existence of competing factors or conformational changes masking the microRNA site, and the possibility that target transcripts are not present in the prediction databases, as is the case for long ncRNAs.
Most genes in the library exhibited low-level expression, only a small number of genes exhibited high-abundance expression.
Here we detected a low-abundance expression of a group of piRNA-like small RNAs in developing cortex of rat based on the sequence mapping to reference libraries (piRNA Bank, http://pirnabank.ibab.ac.in/index.shtml) [ 66].
The higher-order analyses (Regulatory Impact Factor analyses) are built up from the 'bricks' of the more basic analyses (abundance, differential expression, co-expression and differential co-expression).
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