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Then you start working and suddenly you see that there she is, she has absolutely discarded any trappings of being a star, or a diva, this larger than life person.
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In summary, although it is hard to absolutely discard age-associated changes in tissue composition as the underlying mechanism of these common tissue-independent signatures, following Occam's Razor, the evidence does point towards the simplest explanation, which is that gradual age-associated accumulation of DNAm changes does occur independently of cell type.
It reflects a prevailing thought process that has outlived its usefulness, one that absolutely must be discarded and replaced with something new.
This leads to a precise co-chromatography of the H-labelled standard and the P-labelled product formed from Ins P6 in the cell extract (e.g. Figure 1); any sample in which this co-chromatography was not absolutely precise was discarded (except for some blanks, where low levels of radioactivity meant that the correlation was less evident: see below).
Furthermore, in case it is absolutely necessary to discard the stroma gene expression, it might be an option to perform in silico microdissection [ 21- 23].
But as Les Carpenter points out on Yahoo.com, Shanahan has shown absolutely no patience in his search for his next John Elway, leaving a trail of discarded quarterbacks in his wake.
Even food in tin cans should be discarded if the cans got wet during the flood because there is no way to be absolutely certain the food inside is safe.
Instead, you descend between gloriously bleak mountains across icebergs scattered like discarded Polystyrene at a festival of litter, and you land on an unpaved, gravelly runway, at which point my teenage son yelled: "But Dad – there's absolutely nothing here".
They had been discarded".
Condoms torn and discarded.
Not discarded; but atrophied.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com