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This decision means that the direct comparison will be more likely to be statistically significant, but it has no effect on the absolute inconsistency between the direct and indirect comparison.
For analysis across all residues, we use the percentage as defined above (absolute inconsistency) whereas for subsets of residues with particular annotations we report values normalized as a percentage of the overall inconsistency for the same method across all residue types (relative inconsistency).
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Figure 2 shows a plot of the absolute inconsistencies for each of the 8 methods.
To examine the effect of random error, we plotted the absolute value of inconsistency against the inverse of its standard error in a one sided funnel plot.
We used the absolute value of inconsistency because it would usually be arbitrary to decide which of the two interventions being compared was the main treatment of interest (notated as A in the above equations) and which was considered as the active comparator (notated as B).
The relative coefficient (the generalizability coefficient: Eρ 2 ) takes into account rank order inconsistencies while the absolute coefficient (the dependability coefficient:Φ) also includes level inconsistencies [ 27, 28].
The only inconsistency observed was the absolute change in pH from baseline to peak in SBC3, revealing a poor ICC.
Peter Bouckaert, emergencies director for Human Rights Watch, spent several weeks this autumn on the Greek islands and along the Balkan route, and said the inconsistencies of the system have created "absolute chaos".
Consequently, this strand advocates an absolute measure over a relative one, due to the latter's inconsistency.
In contrast, SPA failed to produce uniform results on IVF outcome prediction, and this finding along with protocol inconsistency, indicate, that it is far from being an absolute test for male fertility potential.
The THC was first found in a vial of tap water meant to show an absolute negative result for drugs after a local company reported inconsistencies in drug tests on its employees.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com