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There are some possible explanations for the absent effects.
This was possible with almost absent effects on plasma cholesterol or angiotensinogen.
Besides methodological issues, the absent effects of the problem-solving activities mentioned above could also result from contentual issues.
And so that 2000 study of CoQ10 did not generate meaningful evidence of absent effects; rather, it left us with a rather meaningless absence of evidence.
Certainly, ATM depletion (or that of its activator NBS1) does not influence the cell cycle of undamaged single cells or of syncytia (with absent effects on the frequency of cyclin B1-positive cells, and on the G2/M-linked karyogamy, Fig. 3).
Interactions with drugs, such as ibuprofen, that interfere with aspirin induced COX-1 acetylation may also be a cause of inadequate or absent effects of aspirin (39).
Similar(53)
The absent effect of rituximab on MPGES1 expression suggests a similar limited effect on the expression of MPGES1 inducing cytokines.
In these cases, Kunitz inhibitors with an arginine at position P1 are strongly preferred over those with a P1 lysine [52], [53], thus explaining at least partially the poor or absent effect of boophilin on FXa, FXIIa, uPA and t-PA.
This might explain the absent effect of PEEP in reversing IAP induced FRC decline in the setting of grade IV IAH, respectively.
Relatively high levels of GLP-1 are needed for weight regulation (44), which also explains the absent effect on weight loss during treatment with DPP-4 inhibitors.
With regard to the primary endpoint, the incidence of creatinine-based CIN, several reasons might account for the absent effect of MBL deficiency in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com