It was the absence of ideological rigor in Mr. Franks that prompted Governor Kean to make Mr. Franks his Assembly floor leader.
But maybe the absence of intellectual rigor provides cover for anything the city wants to do under the guise of reaching out.
The phrase connotes an absence of, say, highbrow rigor and difficulty, or, equally, lowbrow flash and perversity.
However, this causes a new problem: if cycling cross-bridges are able to keep the thin filament activated even in the absence of Ca2+, like rigor bridges or Apo-S1, why should relaxation occur at all?
Monomeric, fluorescently labeled dynein331 kDa molecules were bound to surface-immobilized microtubules in the absence of nucleotide, inducing strong "rigor" binding.
In control experiments, designed to test the specificity of MgADP, photolysis of caged ADP in the absence of Mg2+ did not decrease rigor force in either smooth muscle, but rigor force decreased after photolytic release of Mg2+ in the presence of ADP.
The extensive deformation of rigor rear bridges and their complete absence in AMPPNP [27], [56], suggests that the high actin affinity of nucleotide-free myosin extends the limit of acceptable actin azimuth.
Photolytic release of MgADP (25 300 μM) from caged ADP in permeabilized tonic (rabbit femoral artery-Rfa) and phasic (rabbit bladder-Rbl) smooth muscle in high-tension rigor state, in the absence of Ca2+, caused an exponential decline (∼1.5% in Rfa and ∼6% in Rbl) of rigor force, with the rate proportional to the liberated [MgADP].
That the exchange is incomplete can be explained by the fact that under rigor conditions, in the absence of Ca2+, mainly the overlapping region is exchanged but not the nonoverlapping thin filament (30).
