Over time, if a low rate of neuron death continues in the absence of replacement, the neuron population will eventually be reduced by a significant level.
With the gradual withdraw of Global Fund and eventual termination in China in 2013, many of these CBOs is expected to dissolve in the absence of replacement funding from the government [ 377, 378].
The evolution of ago-1a has clearly been driven by strong purifying selection, as detected by branch models in PAML, with extremely low values of ratios of non-synonymous to synonymous substitution rates (dN/dS or ω) and near-absence of replacements for the aphids of the subfamily Aphidinae.
His term on the board expired last year, but he has remained in the absence of a replacement.
What hasn't changed from last year, unfortunately, is the budget's studious vagueness about the details of its proposed tax reform (it calls for lower rates and a broader base without itemizing which of the many popular deductions it wants capped or eliminated) and the absence of any replacement for a repealed Obamacare.
In the case discussed, absence of hormonal replacement (approximately 15 years) would have contributed.
It is only recently that the clinical efficacy of gene therapy has been investigated in the absence of enzyme-replacement therapy.
Materials and methods In this prospective randomized study, we evaluated septic critically ill patients in whom CIV was given for more than 48 h in the absence of renal replacement therapy.
It is worth to note that in PD, patients experimented pain during the Off-period (absence of dopamine replacement therapy) which highlighted the general role for dopamine in pain process.
BMP signaling promotes self-renewal in mouse stem cells when incubated together with Leukemia Inhibitory Factor in the absence of serum replacement or conditioned medium [4].
In contrast, biological elasticity decreases significantly in the absence of hormone replacement therapy.
