The phrase "absence of linkage" is correct and usable in written English.
It can be used in contexts discussing relationships, connections, or associations between concepts, entities, or data points.
Example: "The absence of linkage between the two studies raises questions about the validity of the findings."
Alternatives: "lack of connection" or "non-existence of association".
In the absence of linkage information, we can instead use a "genome-wide coverage" metric computed with the pedigree structure.
Under the absence of linkage, the mod score conforms to a chi-square distribution, with extra degrees of freedom in comparison to the lod score function MacLean et al. 1993.
However, after clone correction, the null hypothesis was not rejected (Table 3), indicating the absence of linkage disequilibrium and therefore suggesting the potential existence of recombination.
We note that the general process of gene prioritization applies to the entire genome and may point to strategies in the absence of linkage knowledge as well for rare Mendelian disorders.
Likewise, the genetic causes of highly complex disorders such as autism or schizophrenia are certain to be numerous, but as true disease genes are identified in these disorders and others, gene-gene correlation analyses should be applied to prioritize additional genes in the absence of linkage or genome-wide association signals.
An absence of linkage between the education and training sectors (universities) and the health services.
A lack of capacity for HSR may manifest itself in multiple ways, such as an insufficient number of skilled researchers to conduct multidisciplinary research, inadequate library or information systems, unsupportive organizational environments, or an absence of linkages to policymakers and decision-makers who form the principal audience for much HSR.
Immobilized phosphonate was characterized by the absence of covalent linkage in Fourier transform infrared spectroscopy and polyanion effect in X-ray diffraction analysis.
Since the benefit of increased R&D would likely flow primarily to the leading R&D centres (the USA, the EU and Japan), the absence of this linkage for purposes of our study of spillovers on India is relatively limited.
While theoretically possible, the accumulated evidence for heritability is strong, with heritability estimates of approximately 80 85% [4], [79], making true absence of genetic linkage within families unlikely.
The absence of additional linkage information means that less variation in the SLK can be allowed when identifying matches.
