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The latter product of segmental gene conversion has been reported for A. marginale but in low frequency, only after host-imposed immune pressure, and with an important fitness disadvantage in the absence of immunity, compared with simple recombinants of whole hypervariable region domains [11], [24].
Dr Jakab added that a "combination of broad geographical distribution of mosquito species that can transmit the virus, the absence of immunity against the virus throughout the world and lack of both a vaccine and rapid, reliable diagnostic tests raises concerns that Zika virus disease will spread globally".
Dr Zsuzanna Jakab, the WHO regional director for Europe, said the "combination of broad geographical distribution of mosquito species that can transmit the virus, the absence of immunity against the virus throughout the world and lack of both a vaccine and rapid, reliable diagnostic tests raises concerns that Zika virus disease will spread globally".
The expert committee examined the virus' recent spread; the broad distribution of Aedes aegypti mosquitos, which can transmit the virus; the lack of vaccines or diagnostic tests and the absence of immunity in newly affected countries.
Again the difference is due to the presence or absence of immunity.
In the vector population, the absence of immunity and rapid demographic turnover mean infection incidence is proportional to population size.
Similar(43)
The life-long, exogenously induced passive immunity compensates the absence of adaptive immunity as mediated by the B-lymphocytes and enables XLA patients to live a fairly normal life.
Thus, in the absence of innate immunity, the adaptive immune system can compensate so that host and bacterial mutualism can be maintained.
Likewise, hosts with adaptive immunity (either fixed or in coexistence) show suicide propensities similar to those expected for equivalent immune efficacies in the absence of adaptive immunity.
Both classes of hosts have the same level of innate immunity and only differ by the presence or absence of adaptive immunity the efficacy of which is kept constant during the simulations.
In addition, 25 healthy individuals with a positive immune response towards PPD in the absence of specific immunity towards ESAT-6 and CFP-10 were analysed (43.3±12.7 years of age, 9 males, 16 females).
More suggestions(16)
absence of immunization
time of immunity
absence of arthritis
absence of respect
existence of immunity
absence of protection
defect of immunity
failure of immunity
absence of resistance
absence of immunisation
absence of relief
absence of waiver
absence of freedom
absence of protecting
absence of antibody
absence of integrity
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