Sentence examples for absence of activated from inspiring English sources

In the absence of activated bone marrow cells, recombinant granulin alone was able to stimulate the growth of indolent tumor cells with an accompanying desmoplastic reaction.

The combined effects of either HSC-derived BMPs and Epo effects on stromal cells in the absence of activated osteoclast activity are likely to lead to a net gain in bone formation.

Further analysis by Kraut-Cohen et al. [60] reveals that, in the absence of activated HER2, PTPRE inhibits the activity of Shc and thus indirectly inhibits the mitogen-activated protein kinase (MAPK) pathway.

The absence of activated caspase-3 expression in T47D and MCF7 cells suggests that essential oil-induced apoptosis may activate a caspase-3-independent pathway similar to taxol-induced apoptosis in breast carcinoma MCF7 cells [ 40].

During sleep, REM and nREM episodes could be differentiated by the presence or absence of activated patterns of EEG in the nCTX (low voltage fast activity: LVFA and HPCC (theta), respectively.

FXa activates prothrombin more than 10-fold more efficiently in conjunction with activated factor V than in the absence of activated factor V, resulting in abundant formation of fibrin and clotting [ 6].

Addition of TGF-beta1 in the absence of activating signals induced the activation of both Smad 3 and p38, detectable at 4 hours and 16 hours of culture (Figure 2).

In this report, we have identified an optimal configuration of ER-LBD-I-SceI fusion protein that provides tight control of I-SceI activity in the absence of activating ligand.

In the absence of activating signals and TGF-beta1, spontaneous activation of p38 MAP kinase as well as Smad 3 was observed (Figure S 1), which may have been caused by the isolation procedure and/or cytokines carried over into the culture.

We previously observed synthetic growth defects in this strain, indicating that the T-loop mutation impairs physiologic Cdk9 function beyond the simple ∼10-fold reduction in kinase activity due to the absence of activating phosphorylation [20].

Nevertheless, several lines of evidence implicate activation of Wnt/β-catenin signalling in serous EOC in the absence of activating mutations in either APC, Axin or β-catenin.