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The phrase "absence of a second" is correct and usable in written English.
It can be used in contexts discussing time, measurement, or comparisons where the lack of a second element is relevant.
Example: "In the absence of a second opinion, we must proceed with caution."
Alternatives: "lack of a second" or "without a second".
Exact(56)
The differences come not just from the absence of a second parent.
Das could opt for the third ruling based on the absence of a second volunteer for contraction.
But in the absence of a second stage of reform, the first stage has unexpectedly strengthened the upper house.
Both experiments demonstrate an extreme form of blindness to a meaningful visual stimulus, even in the absence of a second stimulus that would compete for attentional resources.
He specifically mentioned the lack of creative guile in midfield, an oversupply of centre-forwards and absence of a second decent full-back.
In February 2003, more than 90% of Britons opposed Tony Blair's government joining the invasion of Iraq in the absence of a second UN resolution.
This explains not only the absence of a second Einstein, but also of another Beethoven,.400 hitter in baseball and 100-point game in basketball.
Similar(4)
The gray zone, which might be mistaken for the third way, is an aberration, a state of desperate limitation produced by the absence of a third way.
The pair took their ninth-wicket partnership past 50, batting sedately and taking advantage of the absence of a third man.
Then, tempted by the absence of a third man, he tried to upper cut a bouncer from Rubel Hossain and was caught behind.
In the absence of a first division women's league in the United States, Americans have played in leagues in France, Germany, Norway and Sweden in recent years.
More suggestions(18)
absence of a first
need of a second
failure of a second
time of a second
absence of a next
subject of a second
absence of a secondary
availability of a second
free of a second
non availability of a second
missing of a second
absence of a comprehensive
absence of a solid
absence of a particular
absence of a convincing
absence of a lymphocytic
absence of a real
absence of a distinct
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com