Sentence examples for abrogation from from inspiring English sources

Although this phenotype can depend on the cell type, some mutations affecting this state are observed in numerous cell types and reproduced by our model; for instance, the senescent arrest arises from overexpression of p16INK4a [ 4, 7] and its abrogation from p21 or p16INK4a inactivation [ 7].

(iii) Abrogation of PTC from the neuronal N-Bak mRNA did not lead to its translation.

They are just an initial step away from past abrogation of strategy and delivery to poorly defined, outsourced arrangements, and we need to remain focused on the real prize (the death of the vertical)." As things stand, Whitehall appears intent on preserving the vertical, which means there will be a significant presence for SIAMs.

However, while SMS confers the advantages of higher sensitivity and abrogation of issues stemming from read duplication, the technology has a number of confounding characteristics.

100 ppm CO exposure attenuated neutrophil sequestration within the pulmonary vasculature as well as LPS-induced neutrophilia at 6 hours after LPS, likely due to abrogation of neutrophil mobilisation from bone marrow.

This suggests that MM patients may benefit from the abrogation of this kinase network through the administration of a MEK inhibitor.

IF analysis of centromeric chromatin fibers demonstrates that these cellular and nuclear phenotypes arise specifically from the abrogation of CENP-A and HJURP localization to the centromere.

G2 abrogation prevents cancer cells from repairing DNA damage, forcing them into M phase and the so-called 'mitotic catastrophe' and apoptosis.

The response of cohesin to centromere splitting varied between chromosomes, from complete abrogation of binding (e.g. chromosome 1) to a reduction of cohesin without change to the overall association pattern (e.g. chromosome 3).

Therefore, the hypersensitivity to DNA damage of NHEJ- proficient atm might originate first from cell cycle checkpoint abrogation, enabling cells to divide before complete repair than from DNA repair deficiency per se.

Thus, we demonstrated that treatment of endothelial cells with DHEA in each setting results in an abrogation of VCAM-1 expression from the cell surface at the earliest measurement point (after two hours).